Introduction: It is critically important to prevent infectious disease transmission from the donor to the recipient since annual reports show trending increase of reported disease transmission in United States. We have implemented the deceased donor screening by transplant infectious disease (TxID) team for all solid organ transplant recipients . TxID physicians form part of the multidisciplinary team that evaluate the donornet to provide proper prophylaxis and/or treatments.
Of importance, assessment is not restricted to the pathogens of special interest per OPTN, but includes all potential pathogens. The purpose of this study is to determine the efficacy and integrity of a robust TxID program within a multidisciplinary team in solid organ transplant centers.
Method: This is a retrospective study conducted at one of the biggest solid organ transplant centers in USA. We have checked all electrical medical records and obtained interventions that have been performed based on the donor information between April 1st, 2022 and March 31st, 2023.
Result: We performed 371 kidney and 159 liver transplants during this study period. Around 150 transplant ID consultations occurred at the time of the organ offer; but, TxID consults occurred for all transplant recipients to assess positive culture and abnormal images. TxID declined 8% due to high infectious disease suspicion or confirmation. Also, out of 371 kidney transplants, TxID intervened with detailed medical management in 112 (29.6%); 48/159 (30.2%) for liver transplants. Of note, graft loss or death due to infection within 90 days post-transplant was seen in 3/371 and 2/159 for kidney and liver transplants respectively. None of them were donor-derived.
Since the implementation of the program, we have successfully screened all potential donor-derived infections and reported to UNOS in a timely manner.

Conclusion: Even though, we have forecasted the decrease donor derived infections, our transplant center still continues identified some donor-derived infections; thus providing the proper treatment in a timely manner. We successfully reported donor-derived infections in hopes of avoiding disease transmission from the same donor. Integration of Tx ID in a multidisciplinary team should optimize patient safety across all solid organ transplants.